@article{Arnould2020-bo,

title = {Influence of cardiac hemodynamic variables on retinal vessel 

 density measurement on optical coherence tomography angiography 

 in patients with myocardial infarction},

author = {L Arnould and C Guenancia and P-H Gabrielle and S Pitois and F Baudin and T Pommier and M Zeller and A M Bron and C Creuzot-Garcher and Y Cottin},

year  = {2020},

date = {2020-03-01},

journal = {J. Fr. Ophtalmol.},

volume = {43},

number = {3},

pages = {216–221},

publisher = {Elsevier BV},

abstract = {INTRODUCTION: Quantitative measurements of retinal 

 microvasculature by optical coherence tomography angiography 

 (OCT-A) have been used to assess cardiovascular risk profile. 

 However, to date, there are no studies focusing on OCT-A imaging 

 in the setting of the altered hemodynamic status found in 

 high-risk cardiovascular patients. METHODS: To determine the 

 potential association between retinal vascular density on OCT-A 

 and a comprehensive battery of hemodynamic variables in patients 

 with myocardial infarction (MI) using data from the acute phase 

 and at 3 months follow-up after cardiac rehabilitation. This 

 prospective longitudinal study included patients who presented 

 with MI in the cardiology intensive care unit at Dijon 

 University Hospital. Main outcomes and measurements were retinal 

 vessel density on OCT-A, hemodynamic status based on left 

 ventricular ejection fraction (LVEF), and indexed cardiac output 

 during the acute phase of myocardial infarction and at 3 months 

 follow-up. RESULTS: Overall, 30 patients were included in this 

 pilot study. The median (IQR) age was 64 years (55-71) with 87% 

 men. At admission, the mean (SD) LVEF was 53% (11), and the 

 mean indexed cardiac output was 2.70 (0.83) L/min/m2. On OCT-A, 

 the mean inner retinal vascular density was 19.09 (2.80) mm-1. 

 No significant association was found between retinal vascular 

 density and hemodynamic variables. CONCLUSION: We found no 

 significant association between retinal vascular density on 

 OCT-A and hemodynamic variables in the acute phase of a 

 myocardial infarction or after 3 months of cardiac 

 rehabilitation. Therefore, OCT-A findings do not seem to be 

 influenced by the hemodynamic changes associated with myocardial 

 infarction.},

keywords = {Cardiovascular disease;   R{é}tine, Infarction infarctus du myocarde; Maladie cardiaque   ath{é}roscl{é}rotique; OCT angiographie; Retina, Myocardial infarction, OCT   angiography},

pubstate = {published},

tppubtype = {article}

}