Liste des publications
Publications du département d'ophtalmologie
Bienvenue sur la page dédiée aux publications scientifiques du département d'ophtalmologie du centre médical des Aravis. Notre équipe médicale s'investit activement dans la recherche et l'innovation afin d'améliorer constamment la prise en charge de nos patients. Nos travaux portent sur un large éventail de thématiques, notamment :
Domaines d'expertise
- Les maladies de la cornée, telles que le kératocône, et les techniques chirurgicales associées (greffe de cornée, etc.).
- Les pathologies rétiniennes, comme la DMLA ou le décollement de la rétine, avec une expertise particulière dans les traitements par injections intravitréennes et la chirurgie vitréo-rétinienne.
- L'épidémiologie et la santé publique en ophtalmologie, en utilisant des bases de données nationales pour analyser les tendances et les facteurs de risque de différentes maladies oculaires.
- L'impact des technologies numériques sur la santé oculaire, notamment l'utilisation de la télémédecine pour le dépistage de la rétinopathie diabétique.
Nous sommes fiers de partager ici nos contributions à l'avancement des connaissances en ophtalmologie. N'hésitez pas à consulter nos publications pour en savoir plus sur nos domaines d'expertise et nos recherches en cours.
2022
Ghezala, Inès Ben; Mariet, Anne-Sophie; Benzenine, Eric; Bardou, Marc; Bron, Alain Marie; Gabrielle, Pierre-Henry; Baudin, Florian; Quantin, Catherine; Creuzot-Garcher, Catherine
Association between obstetric complications and intravitreal anti-vascular endothelial growth factor agents or intravitreal corticosteroids Article de journal
Dans: J. Pers. Med., vol. 12, no. 9, p. 1374, 2022.
Résumé | BibTeX | Étiquettes: anti-vascular endothelial growth factor; corticosteroid; drug safety; intravitreal injection; obstetric complication; pharmacoepidemiology; pregnancy
@article{Ben_Ghezala2022-ir,
title = {Association between obstetric complications and intravitreal
anti-vascular endothelial growth factor agents or intravitreal
corticosteroids},
author = {Inès Ben Ghezala and Anne-Sophie Mariet and Eric Benzenine and Marc Bardou and Alain Marie Bron and Pierre-Henry Gabrielle and Florian Baudin and Catherine Quantin and Catherine Creuzot-Garcher},
year = {2022},
date = {2022-08-01},
journal = {J. Pers. Med.},
volume = {12},
number = {9},
pages = {1374},
publisher = {MDPI AG},
abstract = {This nationwide population-based cohort study aimed to describe
the use of intravitreal injections (IVTs) of anti-vascular
endothelial growth factor (anti-VEGF) agents and corticosteroids
in pregnant women in France and to report on the incidence of
obstetric and neonatal complications. All pregnant women in
France who received any anti-VEGF or corticosteroid IVT during
pregnancy or in the month preceding pregnancy from 1 January
2009 to 31 December 2018 were identified in the national
medico-administrative databases. Between 2009 and 2018, there
were 5,672,921 IVTs performed in France. Among these IVTs, 228
anti-VEGF or corticosteroid IVTs were administered to 139 women
during their pregnancy or in the month preceding their
pregnancy. Spontaneous abortion or the medical termination of
pregnancy occurred in 10 women (16.1%) who received anti-VEGF
agents and in one (3.1%) of the women who received corticosteroids (p = 0.09). This is the first national cohort
study of pregnant women treated with anti-VEGF or corticosteroid
IVTs. We found a high incidence of obstetric complications in
pregnant women treated with anti-VEGF or corticosteroid IVTs but
could not demonstrate a statistically significant association
between the intravitreal agents and these complications. These
agents should continue to be used with great caution in pregnant
women.},
keywords = {anti-vascular endothelial growth factor; corticosteroid; drug safety; intravitreal injection; obstetric complication; pharmacoepidemiology; pregnancy},
pubstate = {published},
tppubtype = {article}
}
the use of intravitreal injections (IVTs) of anti-vascular
endothelial growth factor (anti-VEGF) agents and corticosteroids
in pregnant women in France and to report on the incidence of
obstetric and neonatal complications. All pregnant women in
France who received any anti-VEGF or corticosteroid IVT during
pregnancy or in the month preceding pregnancy from 1 January
2009 to 31 December 2018 were identified in the national
medico-administrative databases. Between 2009 and 2018, there
were 5,672,921 IVTs performed in France. Among these IVTs, 228
anti-VEGF or corticosteroid IVTs were administered to 139 women
during their pregnancy or in the month preceding their
pregnancy. Spontaneous abortion or the medical termination of
pregnancy occurred in 10 women (16.1%) who received anti-VEGF
agents and in one (3.1%) of the women who received corticosteroids (p = 0.09). This is the first national cohort
study of pregnant women treated with anti-VEGF or corticosteroid
IVTs. We found a high incidence of obstetric complications in
pregnant women treated with anti-VEGF or corticosteroid IVTs but
could not demonstrate a statistically significant association
between the intravitreal agents and these complications. These
agents should continue to be used with great caution in pregnant
women.
Explorer
Recherche
Ghezala, Inès Ben; Mariet, Anne-Sophie; Benzenine, Eric; Bardou, Marc; Bron, Alain Marie; Gabrielle, Pierre-Henry; Baudin, Florian; Quantin, Catherine; Creuzot-Garcher, Catherine
Association between obstetric complications and intravitreal anti-vascular endothelial growth factor agents or intravitreal corticosteroids Article de journal
Dans: J. Pers. Med., vol. 12, no. 9, p. 1374, 2022.
@article{Ben_Ghezala2022-ir,
title = {Association between obstetric complications and intravitreal
anti-vascular endothelial growth factor agents or intravitreal
corticosteroids},
author = {Inès Ben Ghezala and Anne-Sophie Mariet and Eric Benzenine and Marc Bardou and Alain Marie Bron and Pierre-Henry Gabrielle and Florian Baudin and Catherine Quantin and Catherine Creuzot-Garcher},
year = {2022},
date = {2022-08-01},
journal = {J. Pers. Med.},
volume = {12},
number = {9},
pages = {1374},
publisher = {MDPI AG},
abstract = {This nationwide population-based cohort study aimed to describe
the use of intravitreal injections (IVTs) of anti-vascular
endothelial growth factor (anti-VEGF) agents and corticosteroids
in pregnant women in France and to report on the incidence of
obstetric and neonatal complications. All pregnant women in
France who received any anti-VEGF or corticosteroid IVT during
pregnancy or in the month preceding pregnancy from 1 January
2009 to 31 December 2018 were identified in the national
medico-administrative databases. Between 2009 and 2018, there
were 5,672,921 IVTs performed in France. Among these IVTs, 228
anti-VEGF or corticosteroid IVTs were administered to 139 women
during their pregnancy or in the month preceding their
pregnancy. Spontaneous abortion or the medical termination of
pregnancy occurred in 10 women (16.1%) who received anti-VEGF
agents and in one (3.1%) of the women who received corticosteroids (p = 0.09). This is the first national cohort
study of pregnant women treated with anti-VEGF or corticosteroid
IVTs. We found a high incidence of obstetric complications in
pregnant women treated with anti-VEGF or corticosteroid IVTs but
could not demonstrate a statistically significant association
between the intravitreal agents and these complications. These
agents should continue to be used with great caution in pregnant
women.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
the use of intravitreal injections (IVTs) of anti-vascular
endothelial growth factor (anti-VEGF) agents and corticosteroids
in pregnant women in France and to report on the incidence of
obstetric and neonatal complications. All pregnant women in
France who received any anti-VEGF or corticosteroid IVT during
pregnancy or in the month preceding pregnancy from 1 January
2009 to 31 December 2018 were identified in the national
medico-administrative databases. Between 2009 and 2018, there
were 5,672,921 IVTs performed in France. Among these IVTs, 228
anti-VEGF or corticosteroid IVTs were administered to 139 women
during their pregnancy or in the month preceding their
pregnancy. Spontaneous abortion or the medical termination of
pregnancy occurred in 10 women (16.1%) who received anti-VEGF
agents and in one (3.1%) of the women who received corticosteroids (p = 0.09). This is the first national cohort
study of pregnant women treated with anti-VEGF or corticosteroid
IVTs. We found a high incidence of obstetric complications in
pregnant women treated with anti-VEGF or corticosteroid IVTs but
could not demonstrate a statistically significant association
between the intravitreal agents and these complications. These
agents should continue to be used with great caution in pregnant
women.